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But for a use as an athletic abilities enhancement supplement we have to consider 2 things. The mechanism of human growth hormone and IGF-1 was observed with injections and doses of actual hormones. Many studies have been performed on subject that are being considered not-healthy (such as people with growth hormone deficiency syndrome, or obese, HIV patients, etc.), those studies have found the positive effects of growth hormone supplementation on lean body mass preservation, lipolysis activation, protein breakdown decrease, positive nitrogen balance, among the others.