The use of vitamin B complex injections is not completely harmful to the individual. Under medical supervision, an individual can experience many benefits from using these B complex shots. Many people suffer from vitamin deficiencies which cause health problems. The use of B complex shots can help to alleviate these problems to a certain extent. However, all of this should be done under medical supervision as the health of the individual can be properly monitored. Individuals wishing to use vitamin injections should have a valid reason for this which can only be assessed by a doctor following blood tests and health checks.
Patients in Studies RA-I, RA-II, and RA-III were tested at multiple time points for antibodies to adalimumab during the 6- to 12-month period. Approximately 5% (58 of 1062) of adult RA patients receiving HUMIRA developed low- titer antibodies to adalimumab at least once during treatment, which were neutralizing in vitro . Patients treated with concomitant methotrexate (MTX) had a lower rate of antibody development than patients on HUMIRA monotherapy (1% versus 12%). No apparent correlation of antibody development to adverse reactions was observed. With monotherapy, patients receiving every other week dosing may develop antibodies more frequently than those receiving weekly dosing. In patients receiving the recommended dosage of 40 mg every other week as monotherapy, the ACR 20 response was lower among antibody-positive patients than among antibody-negative patients. The long-term immunogenicity of HUMIRA is unknown.