Free cholesterol, total cholesterol, triglycerides, and phospholipids were measured in each serum sample using enzymatic methods (Roche Chemicals, Indianapolis, IN) ( Phillips et al. 1989 ). Total lipid concentrations were calculated for each sample using published equations ( Bernert et al. 2007 ; Phillips et al. 1989 ). We adjusted for intraindividual variations in serum wet-weight PCB concentrations resulting from fluctuations in serum lipid concentration by including a natural log-transformed total lipid variable as an independent variable in all statistical analyses.
The most common side effect of topical corticosteroid use is skin atrophy. All topical steroids can induce atrophy, but higher potency steroids, occlusion, thinner skin, and older patient age increase the risk. The face, the backs of the hands, and intertriginous areas are particularly susceptible. Resolution often occurs after discontinuing use of these agents, but it may take months. Concurrent use of topical tretinoin (Retin-A) % may reduce the incidence of atrophy from chronic steroid applications. 30 Other side effects from topical steroids include permanent dermal atrophy, telangiectasia, and striae.